
In order to help wet wipe factories better understand the toxicological data of bacteriostatic and bactericidal agents, and design products that comply with regulatory requirements and market demands, wet wipe liquid formulation factories determine suitable preservative and bactericidal systems as well as dosage amounts for customers by combining the characteristics of their own products with user needs.
Challenge: Required to comply with China's *Cosmetic Safety Technical Specification* and EU CPNP filing, while meeting the "non-irritating" claim.
Solution: Adopt a compound system of 1% phenoxyethanol + 0.2% hexylene glycol to replace traditional MIT ingredients; pass the Primary Irritation Index (PII) test with a result <0.2 (extremely mild irritation).
Challenge for a Medical Enterprise's Surgical Disinfection Wipes:Required to kill 99.999% of Staphylococcus aureus within 2 minutes and comply with US EPA pesticide registration requirements.
Solution:
Adopt a composite bactericidal system of 0.5% chlorhexidine acetate + 70% ethanol, combined with sustained-release technology to extend the action
The recommended antiseptic and bactericidal systems have all passed skin irritation tests (such as patch test positive rate <0.1%) and acute toxicity tests (LD50>5000mg/kg), and the bacteriostatic rate remains ≥95% within the 36-month shelf life.
Challenge for a Medical Enterprise's Surgical Disinfection Wipes:
Needs to kill 99.999% of Staphylococcus aureus within 2 minutes and comply with US EPA pesticide registration requirements.
Solution:
A composite bactericidal system of 0.5% chlorhexidine acetate + 70% ethanol is used, combined with sustained-release technology to prolong the action duration.
In addition to baby wipes and disinfectant wipes, we also has some unique wet wipe products. For example, there are special wipes for sensitive skin, which are formulated with multiple natural moisturizing ingredients and a non-irritating formula, suitable for people with sensitive skin. There are also cleaning wipes for glasses, electronic product screens, etc., which have good cleaning effects and anti-static functions.
Technological R&D investment constitutes the core barrier for international brands. From 2022 to 2024, Procter & Gamble China R&D Center applied for a total of 23 patents related to disinfectant slow-release technology. Its microcapsule encapsulation technology extends the bactericidal effect of wet wipes to 72 hours. Johnson & Johnson jointly developed a compound quaternary ammonium salt formula with the Institute of Microbiology of the Chinese Academy of Sciences, which achieves a 99.99% inactivation rate against coronaviruses. This technology has been applied to its medical-grade product line launched in 2024. Third-party testing data shows that the total bacterial count of international brands' products is controlled at <10CFU/g, significantly better than the national standard requirement of ≤200CFU/g. This quality advantage supports them in maintaining a premium space of 30-35%.
For medical wet wipe clients, based on aseptic production standards and medical device regulations (such as ISO 11737), we customize and develop low-irritation and high-stability preservative and bactericidal systems, precisely matching sterilization-grade required dosage amounts;
For baby wet wipe clients, taking EU cosmetic regulations (EC 1223/2009) as the benchmark, we screen natural-source antibacterial ingredients (such as plant essential oil extracts) and scientifically set mild, non-irritating safe dosage ranges.
Customized System Development
Precise Scenario Matching:
Baby Wet Wipes solution:Selected mild system of phenoxyethanol (≤1%) + chlorphenesin (≤0.3%), certified by EU Cosmetic Regulation (EC 1223/2009).
Medical Bactericidal Wet Wipes solution: Adopted fast-acting bactericidal combination of benzalkonium chloride (0.1-0.2%) + ethanol (≥60%), meeting sterilization-grade requirements of ISO 11737.
Eco-Friendly Wet Wipes solution:Plant-based antibacterial agents (e.g., compound of tea polyphenols + citric acid), with 98% biodegradability rate, complying with ECOCERT natural certification.
Synergistic Enhancement Design:Optimized ingredient ratios through orthogonal testing to achieve 30% improvement in antibacterial activity while reducing single-ingredient dosage by 20%.
Let every wet wipe become a benchmark of safety and efficacy —— With our scientific formulations, we empower your products to lead the market consistently.